Frequently Asked Questions:
Q. Where do we park on the morning of the walk?
A. Parking is available along the roadside around site 2a/b
Q. Can I register the morning of the walk?
A. Yes – there will be a registration table set aside for new registrations.
Q. Where do I take my completed pledge forms and registrations that have been entered already?
A. Separate tables will be set up with lettered signs dividing up 4 groups between 2 tables alphabetically to make things go smoothly?
Q. What about the route?
A. We will be going against traffic. The 5k people will walk or run 2 1/2 times around the park. The 3k people will walk 1 1/2 times around the park.
Q. I don’t have access to a computer? Where can I find pledge forms?
A. Contact us at (204) 918-6926 to have pledge forms sent out to you or to arrange a pickup time.
Q. How do I locate site 2 a/b in Kildonan Park?
A. After you pass the Witches Hut, we are on the left hand side of the road…you will see a covered structure on your left.
Q. Will there be water stations along the route?
A. Because you are passing the start line 2 or 3 times during the walk, there is one water station located at the start line on your right side. For the runners, there will be people prepared to hand off the water to you on the run.
Q. Will there be food and water after the walk?
A. Food is supplied by Denny’s (wraps and veggies). Water is being supplied by Co-Operators.
Lynch Syndrome (Hereditary Colorectal and Uterine Cancer)
How common are colorectal and uterine cancer?
Colorectal cancer, which includes colon and rectal cancers, is one of the three most common cancers in the United States. Approximately 145,000 people are diagnosed with colorectal cancer every year. The lifetime risk for developing colorectal can- cer is around 6 percent.
Uterine cancer (also known as endometrial cancer) is not as common as colon cancer, with around 41,000 cases diagnosed per year in the United States. Women have a 3 percent lifetime risk for developing uterine cancer.
What is Lynch Syndrome?
It has been estimated that about 10 percent of all cancer cases are hereditary. This means the individual has inherited an increased likelihood for developing cancer. The most common hereditary colorectal and uterine cancer syndrome, is Lynch syndrome. In families with Lynch Syndrome, people have an increased risk to develop colorectal cancer, and they tend to be diagnosed at an earlier age than the general population. They also have an increased risk to develop uterine and other cancers. In most families with Lynch syndrome, several people will have cancer. It is important to remember that 90 percent of all cancers are not hereditary.
How is Lynch Syndrome inherited?
Inherited information is contained in every cell in our body on structures called chromosomes. We have 46 chromosomes that come in pairs – 23 from our mother and 23 from our father. Each chromosome is made up of thousands of genes. Genes, like chromosomes, come in pairs. They are packages of genetic information (DNA) that act as instructions for making the substances that help our bodies function properly. A change in this genetic information can interfere with proper body functions by causing the gene to no longer work. These gene changes are called mutations.
Recently, four major genes responsible for the Lynch syndrome have been identified. These genes are called MLH1, MSH2, MSH6 and PMS2. These genes are involved in repairing mistakes in the DNA. If a person has inherited a mutation in one of these four genes, their body is unable to properly repair DNA. Mistakes in the DNA may occur when the cell goes through its natural division process. As a person ages, they are exposed to environmental factors which may also cause mistakes in the DNA. If mistakes in the DNA are not corrected, it may affect cell growth and division, which may eventually lead to cancer. Since a person with a Lynch syndrome mutation cannot repair DNA properly, they have an increased risk for developing cancer.
What are the chances of inheriting a mutated Lynch Syndrome gene?
Lynch syndrome is inherited in an autosomal dominant fashion. Autosomal means that both men and women can inherit a Lynch syndrome mutation. Dominant means that it takes only one Lynch syndrome gene mutation to increase the likelihood for developing cancer. All people have two copies of each of the four Lynch syndrome genes, one from each parent. A person who has a parent with a Lynch syndrome mutation, may inherit either that parent’s Lynch syndrome gene with the mutation or that parent’s working Lynch syndrome gene.